during the early 2010s, the USA was struck with the “opioid disaster”, as illicit fentanyl and new synthetic opioids (NSOs) flooded the unlawful drug current market. Benzimidazole opioids are µ-opioid receptor (MOR) agonists with antinociceptive Homes. Even though the potency of Some compounds is similar to that of morphine, the pharmacologica